Class 100 Cleanrooms

ISO 5 Cleanrooms

An ISO 5 Class clean room, also known as Class 100 cleanroom, is a soft- or hard-sided wall manufactured structure that utilizes HEPA filtration systems to maintain air cleanliness levels of a maximum of 100 particles (≥0.5 µm) per cubic meter of inside air. ISO Class 5 cleanroom purification systems must provide filter coverage of 60-70% and a minimum of 300 air changes per hour. The standard air flow rate for a Class 100 clean room is 36-65 CFM per square foot.

Cleanrooms By United produces high-quality modular ISO 5 cleanrooms that meet all your requirements and specifications. We provide the layout, square footage, and features that your project requires. The custom, flexible construction of our ISO Class 5 clean rooms makes them easy to expand, reconfigure, or relocate as your cleanroom needs evolve.

Contact us for more information regarding our Class 100 cleanroom options or call us at 800-959-0878 and we will gladly help with any questions you may have. Cleanrooms By United is your trusted source for advanced, high-efficiency modular ISO 5 clean rooms.

ISO 5 Clean Room Standards

Classifications for cleanrooms range from ISO 1 to ISO 9, with ISO 9 being the “dirtiest” and ISO 1 being the “cleanest.” These classifications are assigned based on the maximum allowable concentration of particles per cubic foot or meter of air. An ISO 5 class cleanroom was previously defined under US Federal Standard 209E but is now defined under ISO 14644-1, however, both are still regularly used as reference points.

US Federal Standard 209E: denotes the number of particles (≥0.5 µm or larger) per cubic foot (f³) of air.
ISO 14644-1: replaced federal standard 209E in 2001 but is still used as a reference. It denotes the number of particles (≥0.1µm to ≥5µm or more) per cubic meter (m³) of air.

ISO 14644-1 Standard for Maximum Number of Particles Permitted/m³ for ISO 5 Cleanrooms

(FED STD 209E Equivalent: Class 100)

≥0.1 µm	≥0.2 µm	≥0.3 µm	≥0.5µm	≥1µm	≥5 µm
100,000	23,7000	102,000	3,520	8,320	293

US FED Standard 209E Maximum Number of Particles Permitted/ft³ for Class 100 Cleanrooms

(ISO 14644-1 Equivalent ISO 5)

≥0.1 µm	≥0.2 µm	≥0.3 µm	≥0.5µm	≥5 µm
			100

Affordable & Flexible Clean Room Design Options

Since they are constructed of hard or soft panels with a hard ceiling, modular cleanroom systems are highly configurable. Soft panel cleanrooms have walls made from clear PVC and one small opening for entering and exiting the area. Hard panel systems consist of prefabricated panels that join to create a square or rectangular room. Hard-walled cleanrooms are fully enclosed and can be fitted with doors, windows, and transfer hatches, just like a permanent cleanroom. Our hard-walled modular cleanrooms include pre-wired UL Classified raceway installation capabilities.

Some of the advantages modular cleanroom systems provide over permanent clean rooms include:

Versatility: A modular cleanrooms can be readily assembled, disassembled, and relocated, often in just a few days or less
Easily reconfigurable: The layout of a modular cleanroom can be rearranged, expanded, retrofit, and/or upgraded.
Cost-effective: Modular cleanrooms are designed and manufactured offsite for a fraction of the cost of permanent construction.
Time Saving: Modular cleanroom systems can be installed onsite in a fraction of the time as permanent construction.
Reduced downtime: Modular cleanroom installation causes far less disruption to daily operations, allowing many users to keep some or all operations running without disruption.
Leasing: If you lease your space, the modular option allows you to uninstall the clean room you need and take it with you if your operation changes locations.
R.O.I.: Because it can be taken down, moved, and re-erected, a modular cleanroom is considered a piece of capital equipment and can be treated as such for taxation purposes.
Cleanliness: A modular cleanroom is the better option for cleanroom requirements above ISO 6 classification. The materials used in these systems do not shed like drywall or metal studs, reducing the level of contamination.

ISO 5 Clean Room Protective Requirements

Clean rooms implement gowning protocols to prevent contamination from people & clothing and to maintain the Class 100 cleanliness classification. Required gowning attire for ISO 5 clean rooms usually includes goggles, lab coats, shoe coverings/booties, beard covering, and head covering. Nitrile, latex or vinyl gloves are also worn to protect sterilized surfaces from contamination.

In addition to gowning requirements, air showers and pass-through chambers are usually incorporated into the design of a Class 100 cleanroom to prevent any contaminants. Recommended gowning protocols for ISO 5 clean rooms can differ based on the application and industry. It is important to work with a clean room consultant to determine the essential cleanroom design components for your specific application. Common ISO Class 5 cleanroom contamination protection measures include:

Product pass thru chambers
HEPA fan filters
Heat welded vinyl or epoxy floors
Gowning/ante rooms & air showers
Air locks
Air handling system & humidity control
Tacky mats
Sealed lighting
Bunny suit, booties & hood requirements
Stainless steel bench & hands-free sink